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Zbtb16tm1.1(EGFP/cre)Aben
Targeted Allele Detail
Nomenclature
Symbol: Zbtb16tm1.1(EGFP/cre)Aben
Name: zinc finger and BTB domain containing 16; targeted mutation 1.1, Albert Bendelac
MGI ID: MGI:5532503
Synonyms: PLZFGFPcre, Zbtb16tm1.1(EGFPcre)Aben
Gene: Zbtb16  Location: Chr9:48565597-48747522 bp, - strand  Genetic Position: Chr9, 26.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:204428
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsAn IRES linked to an EGFP-cre fusion protein and an FRT-flanked neomycin resistance cassette were introduced immediately after the Zbtb16 (Plzf) stop codon (in exon 7) via homologous recombination in C57BL/6J-derived embryonic stem (ES) cells. Mice were bred to ACTB-FLPe animals to excise the neomycin cassette and create the PLZF allele. (J:204428, J:205609)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Zbtb16     Summary of all recombinase alleles driven by Zbtb16.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zbtb16 Mutation:  24 strains or lines available
References
Original:  J:204428 Bendelac A, A cre knockin allele of the Zbtb16 gene. MGI Direct Data Submission. 2014;
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory