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Col1a1tm1(tetO-EML4/ALK)Kkw
Targeted Allele Detail
Nomenclature
Symbol: Col1a1tm1(tetO-EML4/ALK)Kkw
Name: collagen, type I, alpha 1; targeted mutation 1, Kwok-Kin Wong
MGI ID: MGI:5527336
Synonyms: EML4-ALK
Gene: Col1a1  Location: Chr11:94936224-94953042 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166724
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:  69 strains or lines available
References
Original:  J:166724 Chen Z, et al., Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene. Cancer Res. 2010 Dec 1;70(23):9827-9836
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory