Stip1^tm1.2Mamp
Targeted Allele Detail

Summary

• Symbol: Stip1^tm1.2Mamp
• Name: stress-induced phosphoprotein 1; targeted mutation 1.2, Marco A M Prado
• MGI ID: MGI:5527075
• Synonyms: STI1^-
• Gene: Stip1 Location: Chr19:6998070-7017335 bp, - strand Genetic Position: Chr19, 5.15 cM
• Alliance: Stip1^tm1.2Mamp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201097
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 2, exon 3 and the neomycin resistance cassette. Western blot analysis confirmed reduced protein expression in blastocysts. (J:201097)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stip1 Mutation: 36 strains or lines available

References

• Original: J:201097 Beraldo FH, et al., Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein. FASEB J. 2013 Sep;27(9):3594-607
• All: 4 reference(s)