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Usp7tm2Wgu
Targeted Allele Detail
Nomenclature
Symbol: Usp7tm2Wgu
Name: ubiquitin specific peptidase 7; targeted mutation 2, Wei Gu
MGI ID: MGI:5526104
Synonyms: hauspFL
Gene: Usp7  Location: Chr16:8688722-8757067 bp, - strand  Genetic Position: Chr16, 4.28 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:203102
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 6. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. (J:203102)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usp7 Mutation:  58 strains or lines available
References
Original:  J:203102 Kon N, et al., Roles of HAUSP-mediated p53 regulation in central nervous system development. Cell Death Differ. 2011 Aug;18(8):1366-75
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory