Agrp^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Agrp^tm1Dgen
• Name: agouti related neuropeptide; targeted mutation 1, Deltagen
• MGI ID: MGI:5526035
• Gene: Agrp Location: Chr8:106293327-106306477 bp, - strand Genetic Position: Chr8, 53.04 cM, cytoband D1-D2
• Alliance: Agrp^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199803
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An IRES-lacZ-NeoR cassette replaced a 255bp genomic region containing the first coding exon and translational start site. (J:199803)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agrp Mutation: 18 strains or lines available

References

• Original: J:199803 Warne JP, et al., Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein. J Neurosci. 2013 Jul 17;33(29):11972-85
• All: 5 reference(s)