Prkcz^tm1.1Cda
Targeted Allele Detail

Summary

• Symbol: Prkcz^tm1.1Cda
• Name: protein kinase C, zeta; targeted mutation 1.1, Kazuhiro Chida
• MGI ID: MGI:5524242
• Gene: Prkcz Location: Chr4:155344586-155445818 bp, - strand Genetic Position: Chr4, 86.17 cM, cytoband E2
• Alliance: Prkcz^tm1.1Cda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199829
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette was inserted upstream of exon 8. A second loxP site was inserted downstream of exon 9. Cre-mediated recombination removed the neomycin resistance cassette and exons 8 through 9. (J:199829)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcz Mutation: 43 strains or lines available

References

• Original: J:199829 Hirate Y, et al., Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. Curr Biol. 2013 Jul 8;23(13):1181-94
• All: 4 reference(s)