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Transgene Detail
Symbol: Tg(Thy1-GCaMP6s)GP4.3Dkim
Name: transgene insertion GP4.3, Douglas Kim
MGI ID: MGI:5523977
Synonyms: GP4.3
Transgene: Tg(Thy1-GCaMP6s)GP4.3Dkim  Location: unknown  
Strain of Origin:  C57BL/6J
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe mouse promoter drives neuron-specific expression of this transgene that includes a mutagenized green fluorescent calcium indicator (GCaMP6s), woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), and bovine growth hormone (bGH) polyadenylation sequence. GCaMP consists of a circularly permutated green fluorescent protein (cpGFP), the calcium-binding protein calmodulin (CaM), and CaM-interacting M13 peptide. This GCaMP6s variant of GCaMP incorporates a K78H mutation in cpEGFP, as well as T381R, S383T, and R392G mutations in CaM. Line GP4.3 was generated. (J:101977, J:203036)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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