Rr31^tm1.1Ddu
Targeted Allele Detail

Summary

• Symbol: Rr31^tm1.1Ddu
• Name: regulatory region 31; targeted mutation 1.1, Denis Duboule
• MGI ID: MGI:5523218
• Synonyms: del(65)neo-
• Gene: Rr31 Location: Chr2:75269157-75271345 bp Genetic Position: Chr2, Syntenic
• Alliance: Rr31^tm1.1Ddu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199174
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The conserved noncoding sequence 65, CNS(65), located 670 kb away from the Hoxd cluster was replaced with a floxed neomycin resistance cassette. Cre-mediated recombinaiton removed the neomycin resistance cassette and left a single loxP site. (J:199174)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr31 Mutation: 0 strains or lines available

References

• Original: J:199174 Andrey G, et al., A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science. 2013 Jun 7;340(6137):1234167
• All: 1 reference(s)