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Tg(Pmch-cre)1Rck
Transgene Detail
Nomenclature
Symbol: Tg(Pmch-cre)1Rck
Name: transgene insertion 1, Jeffrey M Friedman
MGI ID: MGI:5521470
Synonyms: Pmch-cre, Tg(Pmch-cre)
Transgene: Tg(Pmch-cre)1Rck  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsBacterial artificial chromosome (BAC) library (CHORI) was used to identify a BAC (#RP23-129A21) containing the entire mouse pro-melanin-concentrating hormone (Pmch) gene. This BAC was generated to contain a cre coding sequence downstream from the start codon, and was microinjected into fertilized C57BL/6J oocytes. (J:202805)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pmch     Summary of all recombinase alleles driven by Pmch.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:202805 Jego S, et al., Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus. Nat Neurosci. 2013 Nov;16(11):1637-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory