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Targeted Allele Detail
Symbol: Adgrg6tm1Taki
Name: adhesion G protein-coupled receptor G6; targeted mutation 1, Tetsu Akiyama
MGI ID: MGI:5521368
Synonyms: R-Gpr126-
Gene: Adgrg6  Location: Chr10:14402583-14545179 bp, - strand  Genetic Position: Chr10, 5.43 cM
Hypotrabeculation and thinner ventricular myocardium in Adgrg6tm1Taki/Adgrg6tm1Taki embryonic hearts

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:202002
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 2 has been replaced by a NLS-LacZ cassette and a loxP flanked neo cassette. RT-PCR analysis confrimed the absence of mRNA expression in hearts from homozygous mice. (J:202002)
Generation of the Adgrg6tm1Taki allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgrg6 Mutation:  37 strains or lines available
Original:  J:202002 Patra C, et al., Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16898-903
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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