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Targeted Allele Detail
Symbol: Adgrg6tm1Taki
Name: adhesion G protein-coupled receptor G6; targeted mutation 1, Tetsu Akiyama
MGI ID: MGI:5521368
Synonyms: R-Gpr126-
Gene: Adgrg6  Location: Chr10:14402583-14545179 bp, - strand  Genetic Position: Chr10, 5.43 cM
Hypotrabeculation and thinner ventricular myocardium in Adgrg6tm1Taki/Adgrg6tm1Taki embryonic hearts

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:202002
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 2 has been replaced by a NLS-LacZ cassette and a loxP flanked neo cassette. RT-PCR analysis confrimed the absence of mRNA expression in hearts from homozygous mice. (J:202002)
Generation of the Adgrg6tm1Taki allele
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgrg6 Mutation:  5 strains or lines available
Original:  J:202002 Patra C, et al., Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16898-903
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory