Rbm8a^{tm1(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Rbm8a^{tm1(EUCOMM)Hmgu}
• Name: RNA binding motif protein 8a; targeted mutation 1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5520227
• Gene: Rbm8a Location: Chr3:96537249-96541107 bp, + strand Genetic Position: Chr3, 41.93 cM, cytoband H3
• IMPC: Rbm8a gene page

Mutation origin

• Mutant Cell Lines: HEPD0936_2_A01, HEPD0936_2_A02, HEPD0936_2_A03, HEPD0936_2_A04, HEPD0936_2_A05, HEPD0936_2_A06, HEPD0936_2_A07, HEPD0936_2_A08, HEPD0936_2_A09, HEPD0936_2_A10, HEPD0936_2_A11, HEPD0936_2_A12, HEPD0936_2_B01, HEPD0936_2_B02, HEPD0936_2_B03, HEPD0936_2_B04, HEPD0936_2_B06, HEPD0936_2_B07, HEPD0936_2_B08, HEPD0936_2_B09, HEPD0936_2_B10, HEPD0936_2_B12, HEPD0936_2_C02, HEPD0936_2_C03, HEPD0936_2_C04, HEPD0936_2_C05, HEPD0936_2_C07, HEPD0936_2_C09, HEPD0936_2_C10, HEPD0936_2_C11, HEPD0936_2_D02, HEPD0936_2_D03, HEPD0936_2_D04, HEPD0936_2_D05, HEPD0936_2_D06, HEPD0936_2_D08, HEPD0936_2_D09, HEPD0936_2_D10, HEPD0936_2_D11, HEPD0936_2_D12, HEPD0936_2_E02, HEPD0936_2_E03, HEPD0936_2_E04, HEPD0936_2_E05, HEPD0936_2_E07, HEPD0936_2_E09, HEPD0936_2_E10, HEPD0936_2_E11, HEPD0936_2_E12, HEPD0936_2_F01, HEPD0936_2_F02, HEPD0936_2_F04, HEPD0936_2_F05, HEPD0936_2_F06, HEPD0936_2_F09, HEPD0936_2_F11, HEPD0936_2_G01, HEPD0936_2_G02, HEPD0936_2_G03, HEPD0936_2_G05, HEPD0936_2_G06, HEPD0936_2_G07, HEPD0936_2_G09, HEPD0936_2_G11, HEPD0936_2_G12, HEPD0936_2_H01, HEPD0936_2_H02, HEPD0936_2_H03, HEPD0936_2_H04, HEPD0936_2_H05, HEPD0936_2_H07, HEPD0936_2_H08, HEPD0936_2_H09, HEPD0936_2_H10, HEPD0936_2_H11
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1306 starting at position 96537613 and ending at position 96538919 of Chromosome 3 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm8a Mutation: 8 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)