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Cdh13tm1.1Kry
Targeted Allele Detail
Nomenclature
Symbol: Cdh13tm1.1Kry
Name: cadherin 13; targeted mutation 1.1, Gerard Karsenty
MGI ID: MGI:5519977
Synonyms: Tcadherinfl
Gene: Cdh13  Location: Chr8:118283733-119324921 bp, + strand  Genetic Position: Chr8, 65.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199264
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3. FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombnation removed the neomycin resistance cassette and left exon 3 floxed. (J:199264)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh13 Mutation:  20 strains or lines available
References
Original:  J:199264 Kajimura D, et al., Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metab. 2013 Jun 4;17(6):901-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory