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Esrrbtm1.1Ics
Targeted Allele Detail
Summary
Symbol: Esrrbtm1.1Ics
Name: estrogen related receptor, beta; targeted mutation 1.1, Mouse Clinical Institute
MGI ID: MGI:5519215
Synonyms: ERRbetaL2
Gene: Esrrb  Location: Chr12:86407891-86568402 bp, + strand  Genetic Position: Chr12, 40.49 cM
Alliance: Esrrbtm1.1Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201439
Parent Cell Line:  P1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA conditional mutation was generated by insertion of a loxP site upstream of exon 2 and a loxP- and FRT-flanked neomycin resistance cassette. Recombination removed the selection cassette.
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Esrrb Mutation:  211 strains or lines available
References
Original:  J:201439 Gan Z, et al., Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism. J Clin Invest. 2013 Jun 3;123(6):2564-75
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory