Pygo1^tm1.1Kba
Targeted Allele Detail

Summary

• Symbol: Pygo1^tm1.1Kba
• Name: pygopus 1; targeted mutation 1.1, Konrad Basler
• MGI ID: MGI:5518424
• Gene: Pygo1 Location: Chr9:72832927-72859463 bp, + strand Genetic Position: Chr9, 40.08 cM, cytoband D
• Alliance: Pygo1^tm1.1Kba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198562
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. A loxP site was inserted downstream of the PHD finger coding sequence. Cre-mediated recombination removed the neomycin resistance cassette, the NHD domain and the PHD finger coding sequence. (J:198562)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pygo1 Mutation: 20 strains or lines available

References

• Original: J:198562 Cantu C, et al., The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development. 2013 Jun;140(11):2377-86
• All: 4 reference(s)