Asb2^tm1.1Lutz
Targeted Allele Detail

Summary

• Symbol: Asb2^tm1.1Lutz
• Name: ankyrin repeat and SOCS box-containing 2; targeted mutation 1.1, Pierre Lutz
• MGI ID: MGI:5517670
• Synonyms: ASB2^fl
• Gene: Asb2 Location: Chr12:103287401-103322260 bp, - strand Genetic Position: Chr12, 52.9 cM
• Alliance: Asb2^tm1.1Lutz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200966
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT- and loxP-flanked neomycin resistance cassette was inserted usptream of exon 2. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 4 floxed. (J:200966)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asb2 Mutation: 22 strains or lines available

References

• Original: J:200966 Lamsoul I, et al., ASB2alpha regulates migration of immature dendritic cells. Blood. 2013 Jul 25;122(4):533-41
• All: 4 reference(s)