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Targeted Allele Detail
Symbol: Ahi1tm1.1Xjl
Name: Abelson helper integration site 1; targeted mutation 1.1, Xiao-Jiang Li
MGI ID: MGI:5517460
Gene: Ahi1  Location: Chr10:20952547-21080429 bp, + strand  Genetic Position: Chr10, 9.75 cM, cytoband A3
Germline Transmission:  Earliest citation of germline transmission: J:197136
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 x C57BL/6
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA floxed neo cassette was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 2. Subsequent germline cre expression excised exon 2. (J:166236, J:197136)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ahi1 Mutation:  13 strains or lines available
Original:  J:197136 Weng L, et al., Loss of Ahi1 Affects Early Development by Impairing BM88/Cend1-Mediated Neuronal Differentiation. J Neurosci. 2013 May 8;33(19):8172-8184
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory