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Nr2c2tm1Bbm
Targeted Allele Detail
Nomenclature
Symbol: Nr2c2tm1Bbm
Name: nuclear receptor subfamily 2, group C, member 2; targeted mutation 1, Allan Basbaum
MGI ID: MGI:5517362
Gene: Nr2c2  Location: Chr6:92091418-92173058 bp, + strand  Genetic Position: Chr6, 41.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197895
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. (J:197895)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr2c2 Mutation:  57 strains or lines available
References
Original:  J:197895 Wang X, et al., Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch. Neuron. 2013 Apr 24;78(2):312-24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory