Nos1^tm3Plh
Targeted Allele Detail

Summary

• Symbol: Nos1^tm3Plh
• Name: nitric oxide synthase 1, neuronal; targeted mutation 3, Paul L Huang
• MGI ID: MGI:5516456
• Gene: Nos1 Location: Chr5:118004904-118096905 bp, + strand Genetic Position: Chr5, 57.29 cM, cytoband F
• Alliance: Nos1^tm3Plh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106816
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A conditional allele of Nos1 was generated in which exon 6 is flanked by lox sites. (J:106816)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nos1 Mutation: 85 strains or lines available

References

• Original: J:106816 Gyurko R, et al., Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility. Endocrinology. 2002 Jul;143(7):2767-74
• All: 8 reference(s)