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Hprt1tm11Aird
Targeted Allele Detail
Summary
Symbol: Hprt1tm11Aird
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 11, William C Aird
MGI ID: MGI:5514145
Synonyms: Hprt-vWF2-bGIVS2-lacZ
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1tm11Aird page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168401
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe second intron (intervening sequence 2[IVS2]) of human HBB and lacZ gene replaced the first intron. (J:168401)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1272 strains or lines available
References
Original:  J:168401 Liu J, et al., Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle. Blood. 2011 Jan 6;117(1):342-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory