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Targeted Allele Detail
Symbol: Npc2tm1e.1(EUCOMM)Wtsi
Name: Niemann-Pick type C2; targeted mutation 1e.1, Wellcome Trust Sanger Institute
MGI ID: MGI:5513806
Gene: Npc2  Location: Chr12:84754560-84773112 bp, - strand  Genetic Position: Chr12, 39.37 cM
Mutant Cell Line:  EPD0533_3_A06 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:200814
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
Mutation detailsCre excision of MGI:4451979 tm1e allele removes the promoter-driven neo leaving behind the lacZ reporter (J:200814)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npc2 Mutation:  10 strains or lines available
Original:  J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory