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Dhfrtm1b(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Dhfrtm1b(EUCOMM)Wtsi
Name: dihydrofolate reductase; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5513765
Gene: Dhfr  Location: Chr13:92354783-92389053 bp, + strand  Genetic Position: Chr13, 47.64 cM
Mutation
origin
Mutant Cell Line:  EPD0459_2_H07
Germline Transmission:  Earliest citation of germline transmission: J:200814
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre excision of MGI:4441711 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dhfr Mutation:  9 strains or lines available
References
Original:  J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/07/2020
MGI 6.15
The Jackson Laboratory