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Gad2tm1.1Ksvo
Targeted Allele Detail
Nomenclature
Symbol: Gad2tm1.1Ksvo
Name: glutamic acid decarboxylase 2; targeted mutation 1.1, Karel Svoboda
MGI ID: MGI:5512722
Synonyms: Gad22A-mCherry, Gad2-2A-nls-mcherry, Gad2-T2A-NLS-mCherry
Gene: Gad2  Location: Chr2:22512262-22583889 bp, + strand  Genetic Position: Chr2, 15.15 cM, cytoband A-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a T2A oligopeptide that mediates ribosomal skipping (foot-and-mouth disease virus 2A from the insect Thosea asigna virus), and a nuclear localized mCherry in in-frame after the last codon of the Gad2 gene. A frt-flanked neo was places downstream of the mCherry. Flp-mediated recombination removed the neomycin resistance cassette. (J:221246)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad2 Mutation:  47 strains or lines available
References
Original:  J:221246 Peron SP, et al., A Cellular Resolution Map of Barrel Cortex Activity during Tactile Behavior. Neuron. 2015 May 6;86(3):783-99
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory