Tg(H2-K-Il21)#Nlb
Transgene Detail

Summary

• Symbol: Tg(H2-K-Il21)#Nlb
• Name: transgene insertion, Nathalie Labrecque
• MGI ID: MGI:5512705
• Transgene: Tg(H2-K-Il21)#Nlb Location: unknown
• Alliance: Tg(H2-K-Il21)#Nlb page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K-Il21)#Nlb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il21 (MGI:1890474)

• Mutation details: A mouse Il21 cDNA was placed under the control of the H2-K^b promoter and the Ig enhancer. Thirty-one independent founder lines were produced. Two groups were identified based on length of survival. The original paper analysed mice from founder lines surviving longer than three weeks. (J:126318)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:126318 Allard EL, et al., Overexpression of IL-21 promotes massive CD8(+) memory T cell accumulation. Eur J Immunol. 2007 Nov;37(11):3069-77
• All: 1 reference(s)