About   Help   FAQ
Mgl2tm1.1(HBEGF/EGFP)Aiwsk
Targeted Allele Detail
Nomenclature
Symbol: Mgl2tm1.1(HBEGF/EGFP)Aiwsk
Name: macrophage galactose N-acetyl-galactosamine specific lectin 2; targeted mutation 1.1, Akiko Iwasaki
MGI ID: MGI:5510723
Synonyms: CD301bGFP-DTR, Mgl2DTR, Mgl2DTR-GFP
Gene: Mgl2  Location: Chr11:70130329-70137550 bp, + strand  Genetic Position: Chr11, 42.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201044
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe targeting vector was designed to insert a human diphtheria toxin receptor (DTR)-enhanced green fluorescent protein (EGFP) fusion cassette, followed by a loxP-flanked neomycin (neo) resistance cassette, into exon 2. Cre-mediated recombination removed the neomycin resistance cassette. (J:201044)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgl2 Mutation:  17 strains or lines available
References
Original:  J:201044 Kumamoto Y, et al., CD301b Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity. Immunity. 2013 Sep 25;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory