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Mgl2tm1.1(HBEGF/EGFP)Aiwsk
Targeted Allele Detail
Nomenclature
Symbol: Mgl2tm1.1(HBEGF/EGFP)Aiwsk
Name: macrophage galactose N-acetyl-galactosamine specific lectin 2; targeted mutation 1.1, Akiko Iwasaki
MGI ID: MGI:5510723
Synonyms: CD301bGFP-DTR, Mgl2DTR, Mgl2DTR-GFP
Gene: Mgl2  Location: Chr11:70130329-70137550 bp, + strand  Genetic Position: Chr11, 42.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201044
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe targeting vector was designed to insert a human diphtheria toxin receptor (DTR)-enhanced green fluorescent protein (EGFP) fusion cassette, followed by a loxP-flanked neomycin (neo) resistance cassette, into exon 2. Cre-mediated recombination removed the neomycin resistance cassette. (J:201044)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgl2 Mutation:  17 strains or lines available
References
Original:  J:201044 Kumamoto Y, et al., CD301b(+) dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 2013 Oct 17;39(4):733-43
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory