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Transgene Detail
Symbol: Tg(Col2a1-Prg4)1Brle
Name: transgene insertion 1, Brendan Lee
MGI ID: MGI:5508651
Transgene: Tg(Col2a1-Prg4)1Brle  Location: unknown  
Strain of Origin:  FVB/NJ
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(Col2a1-Prg4)1Brle expresses 1 gene
Mutation detailsA transgenic vector incorporating wild-type tyrosinase Tyr<+>, the mouse gene, postranscriptional regulator element (PRE) element from the woodchuck hepatitis virus (WPRE) and polyA driven by the cartilage-specific mouse Col2a1 promoter. Line 1 was generated. (J:200443)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:200443 Ruan MZ, et al., Proteoglycan 4 expression protects against the development of osteoarthritis. Sci Transl Med. 2013 Mar 13;5(176):176ra34
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory