Tg(Mrgpra3-GFP/cre)#Xzd
Transgene Detail

Summary

• Symbol: Tg(Mrgpra3-GFP/cre)#Xzd
• Name: transgene insertion, Xinzhong Dong
• MGI ID: MGI:5506535
• Synonyms: Mrgpra3^GFP-cre
• Transgene: Tg(Mrgpra3-GFP/cre)#Xzd Location: unknown
• Alliance: Tg(Mrgpra3-GFP/cre)#Xzd page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mrgpra3-GFP/cre)#Xzd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mrgpra3 (MGI:2684085)

• Mutation details: Homologous recombination in bacteria was used to insert an EGFP/cre fusion gene sequence into a BAC (RP23-311C15) containing the Mrgpra3 locus, so that the fusion protein was expressed from the Mrgpra3 promoter. RT-PCR results demonstrated GFP/cre expression only in dorsal root ganglia (DRG) and trigeminal ganglia in adults, consistent with endogenous Mrgpra3 tissue expression. Founder and line number information is not available. (J:197482)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mrgpra3 (mouse) Summary of all recombinase alleles driven by Mrgpra3. Alliance mouse Mrgpra3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:197482 Han L, et al., A subpopulation of nociceptors specifically linked to itch. Nat Neurosci. 2013 Feb;16(2):174-82
• All: 22 reference(s)