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Smarcc2tm1.2Stoy
Targeted Allele Detail
Nomenclature
Symbol: Smarcc2tm1.2Stoy
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; targeted mutation 1.2, Anastassia Stoykova
MGI ID: MGI:5504429
Gene: Smarcc2  Location: Chr10:128459248-128490482 bp, + strand  Genetic Position: Chr10, 76.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197141
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 6. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neomycin resistance cassette and left exons 6 and 7 floxed. Cre-mediated recombination removed exons 6 and 7. (J:197141)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarcc2 Mutation:  40 strains or lines available
References
Original:  J:197141 Tuoc TC, et al., Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell. 2013 May 13;25(3):256-69
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory