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Targeted Allele Detail
Symbol: Map2k1tm1Bacc
Name: mitogen-activated protein kinase kinase 1; targeted mutation 1, Manuela Baccarini
MGI ID: MGI:5504398
Synonyms: Mek1f
Gene: Map2k1  Location: Chr9:64185770-64253605 bp, - strand  Genetic Position: Chr9, 34.55 cM
Germline Transmission:  Earliest citation of germline transmission: J:199705
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neomycin resistance cassette was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. (J:199705)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map2k1 Mutation:  93 strains or lines available
Original:  J:199705 Catalanotti F, et al., A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal. Nat Struct Mol Biol. 2009 Mar;16(3):294-303
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory