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Rasd1tm1.1Snyd
Targeted Allele Detail
Nomenclature
Symbol: Rasd1tm1.1Snyd
Name: RAS, dexamethasone-induced 1; targeted mutation 1.1, Solomon Snyder
MGI ID: MGI:5502750
Gene: Rasd1  Location: Chr11:59963181-59964944 bp, - strand  Genetic Position: Chr11, 37.81 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195135
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 1, exon 2 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:195135)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasd1 Mutation:  11 strains or lines available
References
Original:  J:195135 Chen Y, et al., Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. J Neurosci. 2013 Feb 20;33(8):3582-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory