Dp(19Lbx1-Fgf8)2Fsp
Targeted Allele Detail

Summary

• Symbol: Dp(19Lbx1-Fgf8)2Fsp
• Name: duplication, Chr 19, Francois Spitz 2
• MGI ID: MGI:5501272
• Synonyms: DUP(L-F8)
• Gene: Dp(19Lbx1-Fgf8)2Fsp Location: Chr19:45221123-45731354 bp Genetic Position: Chr19, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196292
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Duplication, Insertion
• Dp(19Lbx1-Fgf8)2Fsp involves 12 genes/genome features (Lbx1, 1700016H03Rik, Btrc ...) View all
• Mutation details: TAMERE (targeted meiotic recombination) between Lbx1^tm2Cbm and Fgf8^tm1.4Mrt duplicated the intervening sequence (including Lbx1, 1700016H03Rik, Btrc, Gm19639, Poll, Dpcd, Fbxw4, Gm17018, 4933429K18Rik and Fgf8). (J:196292)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dp(19Lbx1-Fgf8)2Fsp Mutation: 0 strains or lines available

References

• Original: J:196292 Marinic M, et al., An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev Cell. 2013 Mar 11;24(5):530-42
• All: 1 reference(s)