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In(19Fgf8;Pitx3)1Fsp
Targeted Allele Detail
Summary
Symbol: In(19Fgf8;Pitx3)1Fsp
Name: inversion, Chr 19, Francois Spitz 1
MGI ID: MGI:5501271
Synonyms: In(19Fgf8-Pitx3)1Fsp, INV(F8-P3)
Gene: In(19Fgf8;Pitx3)1Fsp  Location: unknown  Genetic Position: Chr19, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196292
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Inversion
  In(19Fgf8;Pitx3)1Fsp involves 24 genes/genome features (A013, D19Ertd132e, D19Ertd409e ...) View all
 
Mutation detailsSTRING (sequential targeted recombination induced genomic rearrangement) between Fgf8tm1.4Mrt and Pitx3tm1Mli inverted the intervening sequence (Npm3, Gm15491, Mgea5, Kcnip2, 9130011E15Rik, Hps6, Ldb1, Pprc1, Nolc1 and Elovl3). (J:196292)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any In(19Fgf8;Pitx3)1Fsp Mutation:  0 strains or lines available
References
Original:  J:196292 Marinic M, et al., An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev Cell. 2013 Mar 11;24(5):530-42
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory