Fbxw4^tm1Fsp
Targeted Allele Detail

Summary

• Symbol: Fbxw4^tm1Fsp
• Name: F-box and WD-40 domain protein 4; targeted mutation 1, Francois Spitz
• MGI ID: MGI:5501257
• Synonyms: NeoInsLac, SHFM-SB0-InsLacNeo
• Gene: Fbxw4 Location: Chr19:45566693-45648751 bp, - strand Genetic Position: Chr19, 38.75 cM
• Alliance: Fbxw4^tm1Fsp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196292
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A Sleeping Beauty cargo transgene was targeted downstream of exon 2 by homologous recombination. It contained a loxP site, lacZ gene, lox2272 site, insulator from HSS4 site of chicken beta-globin locus, loxP site, FRT-flanked neomycin (neo) resistance cassette and lox2272 site. (J:196292)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxw4 Mutation: 28 strains or lines available

References

• Original: J:196292 Marinic M, et al., An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev Cell. 2013 Mar 11;24(5):530-42
• All: 1 reference(s)