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Dbitm1Kier
Targeted Allele Detail
Nomenclature
Symbol: Dbitm1Kier
Name: diazepam binding inhibitor; targeted mutation 1, Ann Kier
MGI ID: MGI:5498509
Gene: Dbi  Location: Chr1:120041010-120048808 bp, - strand  Genetic Position: Chr1, 52.65 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198622
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 1 and 2. QRT-PCR confirmed the absence of transcript expression in E2.5 morulas. (J:198622)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dbi Mutation:  20 strains or lines available
References
Original:  J:198622 Landrock D, et al., Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice. Lipids. 2010 Jul;45(7):567-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory