Samd14^{tm2e(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Samd14^{tm2e(EUCOMM)Hmgu}
• Name: sterile alpha motif domain containing 14; targeted mutation 2e, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5497190
• Gene: Samd14 Location: Chr11:94900705-94916913 bp, + strand Genetic Position: Chr11, 59.01 cM
• IMPC: Samd14 gene page

Mutation origin

• Mutant Cell Lines: HEPD0875_7_A02, HEPD0875_7_A05, HEPD0875_7_A07, HEPD0875_7_A09, HEPD0875_7_A11, HEPD0875_7_A12, HEPD0875_7_B01, HEPD0875_7_B02, HEPD0875_7_B03, HEPD0875_7_B04, HEPD0875_7_B05, HEPD0875_7_B06, HEPD0875_7_B07, HEPD0875_7_B08, HEPD0875_7_B09, HEPD0875_7_B10, HEPD0875_7_B11, HEPD0875_7_C01, HEPD0875_7_C02, HEPD0875_7_C06, HEPD0875_7_C08, HEPD0875_7_C09, HEPD0875_7_C10, HEPD0875_7_D01, HEPD0875_7_D02, HEPD0875_7_D03, HEPD0875_7_D04, HEPD0875_7_D05, HEPD0875_7_D06, HEPD0875_7_D07, HEPD0875_7_D08, HEPD0875_7_D09, HEPD0875_7_D10, HEPD0875_7_D11, HEPD0875_7_D12, HEPD0875_7_E01, HEPD0875_7_E02, HEPD0875_7_E03, HEPD0875_7_E04, HEPD0875_7_E05, HEPD0875_7_E06, HEPD0875_7_E07, HEPD0875_7_E08, HEPD0875_7_E10, HEPD0875_7_E11, HEPD0875_7_E12, HEPD0875_7_F01, HEPD0875_7_F02, HEPD0875_7_F03, HEPD0875_7_F04, HEPD0875_7_F05, HEPD0875_7_F07, HEPD0875_7_F09, HEPD0875_7_F11, HEPD0875_7_G02, HEPD0875_7_G04, HEPD0875_7_G05, HEPD0875_7_G09, HEPD0875_7_G10, HEPD0875_7_G11, HEPD0875_7_G12, HEPD0875_7_H01, HEPD0875_7_H03, HEPD0875_7_H04, HEPD0875_7_H05, HEPD0875_7_H06, HEPD0875_7_H07, HEPD0875_7_H08, HEPD0875_7_H09, HEPD0875_7_H10, HEPD0875_7_H11, HEPD0875_7_H12
• Germline Transmission: Unknown
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 94909702 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Samd14 Mutation: 18 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)