Myh14^tm3.1Rsad
Targeted Allele Detail

Summary

• Symbol: Myh14^tm3.1Rsad
• Name: myosin, heavy polypeptide 14; targeted mutation 3, Robert S Adelstein
• MGI ID: MGI:5496395
• Synonyms: NMIIC-GFP
• Gene: Myh14 Location: Chr7:44255227-44320267 bp, - strand Genetic Position: Chr7, 28.85 cM, cytoband B2
• Alliance: Myh14^tm3.1Rsad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198338
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A floxed neo resistance cassette was inserted in intron 39 and an EGFP sequence was inserted in exon 41 just downstream of the stop codon. The resistance cassette was subsequently removed by crossing properly targeted mice to cre expressing mice. (J:198338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myh14 Mutation: 82 strains or lines available

References

• Original: J:198338 Ebrahim S, et al., NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol. 2013 Apr 22;23(8):731-6
• All: 2 reference(s)