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Kif7dda
Chemically induced Allele Detail
Nomenclature
Symbol: Kif7dda
Name: kinesin family member 7; disorganized diaphragm allele
MGI ID: MGI:5495412
Synonyms: dd, Kif7dd
Gene: Kif7  Location: Chr7:79698098-79715720 bp, - strand  Genetic Position: Chr7, 45.09 cM, cytoband D2
Multiple developmental defects associated with syndromic congenital diaphragmatic hernia in Kif7dda/Kif7dda embryos

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  A/J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
    ENU induced an A to T nonsense mutation at position 2002 creating a premature stop in exon 8. (J:197449)
N-ethyl-N nitrosourea induced an A to T transversion generating the Kif7dda allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif7 Mutation:  4 strains or lines available
References
Original:  J:197449 Coles GL, et al., Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia. Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1898-905
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory