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Snai3tm2.1Grid
Targeted Allele Detail
Nomenclature
Symbol: Snai3tm2.1Grid
Name: snail family zinc finger 3; targeted mutation 2.1, Tom Gridley
MGI ID: MGI:5495409
Synonyms: Snai3null
Gene: Snai3  Location: Chr8:123180947-123187472 bp, - strand  Genetic Position: Chr8, 71.07 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198115
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-neo-FRT-loxP cassette was introduced to intron 1, and a second loxP site was place 5' of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. QRT-PCR confirmed the absence of transcript expression in embryos. (J:198115)
Construction of the Snai3tm2.1Grid and Snai3tm2.2Grid alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snai3 Mutation:  11 strains or lines available
References
Original:  J:198115 Bradley CK, et al., The snail family gene snai3 is not essential for embryogenesis in mice. PLoS One. 2013;8(6):e65344
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory