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Targeted Allele Detail
Symbol: Snai3tm2.1Grid
Name: snail family zinc finger 3; targeted mutation 2.1, Tom Gridley
MGI ID: MGI:5495409
Synonyms: Snai3null
Gene: Snai3  Location: Chr8:123180947-123187472 bp, - strand  Genetic Position: Chr8, 71.07 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:198115
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsAn FRT-neo-FRT-loxP cassette was introduced to intron 1, and a second loxP site was place 5' of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. QRT-PCR confirmed the absence of transcript expression in embryos. (J:198115)
Construction of the Snai3tm2.1Grid and Snai3tm2.2Grid alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snai3 Mutation:  11 strains or lines available
Original:  J:198115 Bradley CK, et al., The snail family gene snai3 is not essential for embryogenesis in mice. PLoS One. 2013;8(6):e65344
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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