Bcar1^tm2.1Homy
Targeted Allele Detail

Summary

• Symbol: Bcar1^tm2.1Homy
• Name: breast cancer anti-estrogen resistance 1; targeted mutation 2.1, Hiroaki Honda
• MGI ID: MGI:5494134
• Gene: Bcar1 Location: Chr8:112437106-112470441 bp, - strand Genetic Position: Chr8, 57.98 cM, cytoband D3
• Alliance: Bcar1^tm2.1Homy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195063
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was floxed. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:195063)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcar1 Mutation: 26 strains or lines available

References

• Original: J:195063 Akimoto T, et al., Skeletal muscle adaptation in response to mechanical stress in p130cas-/- mice. Am J Physiol Cell Physiol. 2013 Mar;304(6):C541-7
• All: 5 reference(s)