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Tg(Prnp-CCS)17Jlel
Transgene Detail
Nomenclature
Symbol: Tg(Prnp-CCS)17Jlel
Name: transgene insertion 17, Jeffrey L Elliott
MGI ID: MGI:5492387
Transgene: Tg(Prnp-CCS)17Jlel  Location: unknown  
Transgene
origin
Strain of Origin:  B6SJLF1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Prnp-CCS)17Jlel expresses 1 gene
 
Mutation detailsHuman wild type copper chaperone for SOD1 cDNA was cloned into a mouse prion protein promoter construct. Line 17 showed the highest levels of expression in the spinal cord. (J:120361)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:120361 Son M, et al., Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6072-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory