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Asic1tm1.1Ccli
Targeted Allele Detail
Nomenclature
Symbol: Asic1tm1.1Ccli
Name: acid-sensing (proton-gated) ion channel 1; targeted mutation 1.1, Cheng-Chang Lien
MGI ID: MGI:5490899
Synonyms: ASIC1aflx
Gene: Asic1  Location: Chr15:99670368-99701130 bp, + strand  Genetic Position: Chr15, 56.13 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193892
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:193892)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asic1 Mutation:  4 strains or lines available
References
Original:  J:193892 Wu PY, et al., Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory. J Neurosci. 2013 Jan 30;33(5):1828-32
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory