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Targeted Allele Detail
Symbol: Rettm6.2Vpa
Name: ret proto-oncogene; targeted mutation 6.2, Vassilis Pachnis
MGI ID: MGI:5489748
Gene: Ret  Location: Chr6:118151745-118197718 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Germline Transmission:  Earliest citation of germline transmission: J:195828
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA floxed neo cassette was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:195828)
Generation of the Rettm6.1Vpa and Rettm6.2Vpa alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ret Mutation:  35 strains or lines available
Original:  J:195828 Almeida AR, et al., RET/GFRalpha signals are dispensable for thymic T cell development in vivo. PLoS One. 2012;7(12):e52949
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory