About   Help   FAQ
Abhd12tm1Crv
Targeted Allele Detail
Nomenclature
Symbol: Abhd12tm1Crv
Name: abhydrolase domain containing 12; targeted mutation 1, Benjamin F Cravatt
MGI ID: MGI:5487621
Gene: Abhd12  Location: Chr2:150832493-150904741 bp, - strand  Genetic Position: Chr2, 74.74 cM
Age-dependent increase in microglial activation in Abhd12tm1Crv/Abhd12tm1Crv brain

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193716
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Abhd12tm1Crv allele
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abhd12 Mutation:  6 strains or lines available
References
Original:  J:193716 Blankman JL, et al., ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1500-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory