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Targeted Allele Detail
Symbol: Rbbp8tm1.1Thl
Name: retinoblastoma binding protein 8, endonuclease; targeted mutation 1.1, Thomas Ludwig
MGI ID: MGI:5484516
Synonyms: CtIPco
Gene: Rbbp8  Location: Chr18:11633276-11743207 bp, + strand  Genetic Position: Chr18, 5.85 cM
Germline Transmission:  Earliest citation of germline transmission: J:194603
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExon 2, which encodes the N-terminal 36 amino acids and contains the translation initiation site, was floxed. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of exon 2. (J:194603)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbbp8 Mutation:  27 strains or lines available
Original:  J:194603 Bothmer A, et al., Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. J Exp Med. 2013 Jan 14;210(1):115-23
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory