Impa2^tm1.1Tohn
Targeted Allele Detail

Summary

• Symbol: Impa2^tm1.1Tohn
• Name: inositol monophosphatase 2; targeted mutation 1.1, Tetsuo Ohnishi
• MGI ID: MGI:5474836
• Gene: Impa2 Location: Chr18:67422246-67454375 bp, + strand Genetic Position: Chr18, 39.92 cM
• Alliance: Impa2^tm1.1Tohn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193924
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxp site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:193924)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Impa2 Mutation: 28 strains or lines available

References

• Original: J:193924 Ohnishi T, et al., Human myo-inositol monophosphatase 2 rescues the nematode thermotaxis mutant ttx-7 more efficiently than IMPA1: functional and evolutionary considerations of the two mammalian myo-inositol monophosphatase genes. J Neurochem. 2013 Mar;124(5):685-94
• All: 1 reference(s)