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Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ming-Jer Tsai
MGI ID: MGI:5474793
Synonyms: CAG-S-hCOUP-TFI
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077244 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162256
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts expresses 1 gene
 
Mutation detailsA conditional over-expression cassette was inserted into the locus. The cassette contains a CAG promoter, floxed STOP cassette, FLAG- and myc-tagged human cDNA and polyadenylation sequence. (J:162256)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  504 strains or lines available
References
Original:  J:162256 Wu SP, et al., Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Mol Endocrinol. 2010 Jun;24(6):1297-304
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory