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Tg(Tagln-SLC6A4)#Edd
Transgene Detail
Nomenclature
Symbol: Tg(Tagln-SLC6A4)#Edd
Name: transgene insertion, Saadia Eddahibi
MGI ID: MGI:5474459
Synonyms: SM22-5-HTT+
Transgene: Tg(Tagln-SLC6A4)#Edd  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Tagln-SLC6A4)#Edd expresses 1 gene
 
Mutation detailsThe murine taglin (Sm22) promoter (2191 bp starting 2126 bp before the start site) drives the expression of the human SLC6A4 (5-HTT) gene. RTQ-PCR and Western blot confirm expression in the lungs. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:144126)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:144126 Guignabert C, et al., Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res. 2006 May 26;98(10):1323-30
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory