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Nmrk2tm1.1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Nmrk2tm1.1(KOMP)Vlcg
Name: nicotinamide riboside kinase 2; targeted mutation 1.1, Velocigene
MGI ID: MGI:5471953
Gene: Nmrk2  Location: Chr10:81198170-81202051 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Mutation
origin
Mutant Cell Line:  10509A-B6
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2634bp between positions 80662085-80664718 of Chromosome 10 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nmrk2 Mutation:  15 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory