C1qb^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: C1qb^{tm1.1(KOMP)Vlcg}
• Name: complement component 1, q subcomponent, beta polypeptide; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5471254
• Gene: C1qb Location: Chr4:136607440-136613498 bp, - strand Genetic Position: Chr4, 69.05 cM
• Alliance: C1qb^{tm1.1(KOMP)Vlcg} page
• IMPC: C1qb gene page

Mutation origin

• Mutant Cell Line: 10211A-E7
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2016bp between positions 136436204-136438219 of Chromosome 4 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:

37 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any C1qb Mutation: 12 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)