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Tg(Gast-EGFP)1Tcw
Transgene Detail
Nomenclature
Symbol: Tg(Gast-EGFP)1Tcw
Name: transgene insertion 1, Timothy C Wang
MGI ID: MGI:5470177
Transgene: Tg(Gast-EGFP)1Tcw  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe ENSEMBL 129S7/AB2.2-derived mouse genomic BAC clone bMQ262f21, encoding full-length gastrin, was modified to express EGFP from the Gast promoter. The open reading frame after the ATG start codon located in exons 2 and 3 was replaced by an EGFP-FRT-PGK-neomycin-FRT cassette. The PGK-neomycin cassette was removed via transfection with an arabinose-induced FLP recombinase plasmid. Line 1 was generated. (J:168390)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:168390 Takaishi S, et al., In vivo analysis of mouse gastrin gene regulation in enhanced GFP-BAC transgenic mice. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G334-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory