Tg(CMV-tTA,tetO-Stxbp3)40Jpes
Transgene Detail

Summary

• Symbol: Tg(CMV-tTA,tetO-Stxbp3)40Jpes
• Name: transgene insertion 40, Jeffrey E Pessin
• MGI ID: MGI:5470157
• Synonyms: Munc18c Tg, Tg(CMV-tTA,tetO-Stxbp3a)40Jepn
• Transgene: Tg(CMV-tTA,tetO-Stxbp3)40Jpes Location: unknown
• Alliance: Tg(CMV-tTA,tetO-Stxbp3)40Jpes page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Transactivator)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A transgene was inserted in which the Stxbp3a (Munc18c) gene sequence was placed under the control of the human cytomegalovirus (CMV) early enhancer and promoter. Mice of this line designated 14140/2 everexpressed Stxbp3a by seven fold. (J:84653, J:130386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:84653 Spurlin BA, et al., Insulin resistance in tetracycline-repressible Munc18c transgenic mice. Diabetes. 2003 Aug;52(8):1910-7
• All: 2 reference(s)